Who/tdr Scientific Working Group on ‘rna Interference as a Means of Identifying Drug Targets for Filariasis’ Report
نویسندگان
چکیده
Control and treatment of these infections is difficult: no vaccines are available, vector control programs have ceased or are threatened by insecticide resistance, and the repertoire of effective drugs is very limited. Onchocerciasis is currently treated with ivermectin; the drugs used for lymphatic filariasis are albendazole, diethylcarbamazine (DEC) and ivermectin. None of these is effective in killing the long-lived adult worms (macrofilariae) and the treatments are therefore aimed at reducing transmission and pathology.
منابع مشابه
RNAi-based discovery and validation of new drug targets in filarial nematodes.
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